Adipose and skeletal muscle tissues have GLUT4, a type of GLUT which is present in the plasma membrane only when blood glucose concentration is high (e.g., after a carbohydrate-rich meal).

Dr Ivo Lieberam from King's College London is leading a diabetes research project that has been awarded a total of £1.2m in ...

Another major goal of this project is to understand the roles of SNAREs and their regulators (chaperones) in metabolic regulation and the pathogenesis of metabolic diseases, primarily using ...

Wan, C., Puscher, H., Ouyang, Y., Wu, J., Tian, Y., Li, S., Yin, Q., Shen, J. (2024) An AAGAB-to-CCDC32 handover mechanism controls the assembly of the AP2 adaptor ...

In this context, existing evidence has shown an involvement of insulin-controlled glucose transporter GLUT4 in modulating ...

This enzyme enhances insulin sensitivity by promoting the movement of glucose transporter 4 (GLUT4) to the cell membrane, ...

Cold-induced skeletal muscle glucose uptake tended to increase upon cold acclimation, which was paralleled by increased basal GLUT4 localization in the sarcolemma, as assessed through muscle biopsies.

By limiting fluctuations in blood sugar, Plantsulin improves energy and vitality, supports healthy digestion, enhances blood ...

FAO is catalyzed by the mitochondrial trifunctional protein (MTP) and, if overloaded, generates ROS. ROS are boosted during ...

MonoB1 FITC-insulin conjugate was also compared to native insulin by examining cell surface GLUT4 in C2C12 skeletal muscle cells. No significant difference in the cellular response was observed for ...